Prof. Dr. Hikmet Akkız’ın çalışmaları, birçok prestijli uluslararası yayın organı tarafından yayımlanmıştır.
Uluslararası Yayınlar
Expression of apoptosis- and vitamin D pathway-related genes in hepatocellular carcinoma.
Fingas CD, Altinbas A, Schlattjan M, Beilfuss A, Sowa JP, Sydor S, Bechmann LP, Ertle J, Akkiz H, Herzer K, Paul A, Gerken G, Baba HA, Canbay A.
Digestion. 2013;87(3):176-81. doi: 10.1159/000348441. Epub 2013 Apr 27.
PMID: 23635474
CHK2 1100delC, IVS2+1G>A and I157T mutations are not present in hepatocellular cancer cases from a Turkish population.
Bayram S, Akkiz H, Topaktaş M.
Gene. 2013 Jan 10;512(2):232-6. doi: 10.1016/j.gene.2012.10.045. Epub 2012 Oct 26.
PMID: 23107771
Lack of an association of programmed cell death-1 PD1.3 polymorphism with risk of hepatocellular carcinoma susceptibility in Turkish population: a case-control study.
Bayram S, Akkiz H, Ülger Y, Bekar A, Akgöllü E, Yıldırım S.
Gene. 2012 Dec 15;511(2):308-13. doi: 10.1016/j.gene.2012.09.119. Epub 2012 Oct 4.
PMID: 23041554
Acute liver failure. Altınbaş A. Beckman LP, Akkiz H, Gerken G, Canbay A. Hepatology 2012.
CHEK2 1100delC, IVS2+1G>A and I157T mutations are not present in colorectal cancer cases from Turkish population.
Bayram S, Topaktaş M, Akkiz H, Bekar A, Akgöllü E.
Cancer Epidemiol. 2012 Apr 19. [Epub ahead of print] PMID: 22521562
The significance of Exonuclease 1 K589E polymorphism on hepatocellular carcinoma susceptibility in the Turkish population: a case-control study.
Bayram S, Akkiz H, Bekar A, Akgöllü E, Yıldırım S.
Mol Biol Rep. 2011 Dec 29. [Epub ahead of print] PMID: 22205538 DOI: 10.1007/s1103-011-1406-x
Higher Hepatis C virus concentration in platelets than in plasma in a patient with ITP.
Onan E, Uskudar O, Coşkun Y, Akkiz H.
Platelets.2011.Oct.19. PMID:22010990 doi:10.3109/09537104.2011.625457
Vitamin D ameliorates stress ligand expression elicited by free fatty acids in the hepatic stellate cell line LX-2.
Canbay A, Seydel S, Beilfuss A, Kahraman A, Aksoy K, Gerken G, Akkiz H
TurkJ.Gastroenterol.2011.Aug;22(4):400-7. PMID:21948571 doi:0.4318/tjg.2011.0254
No Association of Pre-microRNA-146a rs2910164 Polymorphism and Risk of Hepatocellular Carcinoma Development in Turkish Population: A Case-control study Akkiz H, Bayram S, Bekar A, Akgöllü E, Üsküdar O, Sandıkçı M
Gene. 2011 Oct 15;486(1-2):104-9. Epub 2011 Jul 23. PMID: 21807077 doi.org/10.1016/j.gene.2011.07.006
A functional polymorphism in pre-microRNA-196a-2 contributes to the susceptibility of hepatocellular carcinoma in a Turkish population: a case-control study. Akkiz H, Bayram S, Bekar A, Akgöllü E, Ülger Y
J Viral Hepat. 2011 Jul;18(7):e399-407. doi: 10.1111/j.1365-2893.2010.01414.x. Epub 2010 Dec 23, PMID: 21692953
p53 codon 72 polymorphism is associated with susceptibility to hepatocellular carcinoma in the Turkish population: a case-control study.
Sümbül AT, Akkiz H, Bayram S, Bekar A, Akgöllü E, Sandıkçı M.
Mol Biol Rep. 2011 May 24. [Epub ahead of print], PMID: 21607615
The association between the survivin -31G/C promoter polymorphism and hepatocellular carcinoma risk in a Turkish population.
Bayram S, Akkiz H, Bekar A, Akgöllü E.
Cancer Epidemiol. 2011 Dec;35(6):555-9. Epub 2011 Feb 5.PMID: 21296634
doi:10.1016/j.canep.2011.01.004
New therapeutic option with N-acetylcysteine for primary sclerosing cholangitis: two case reports.
Ozdil B, Cosar A, Akkiz H, Sandikci M, Kece C.
Am J Ther. 2011 May;18(3):e71-4, PMID: 20019586
Genetic Variation in the MicroRNA-499 Gene and Hepatocellular Carcinoma Risk in a Turkish Population: Lack of Any Association in a Case-Control Study. Akkiz H, Bayram S, Bekar A, Akgollu E, Uskudar O.
Asian Pac J Cancer Prev. 2011;12(11):3107-12. PMID: 22393998
Atherosclerosis and acetylsalicylic acid are independent risk factors for hemorrhage in patients with gastric or duodenal ulcer.
Ozdil B, Coşar A, Akkiz H, Sandıkçı M.
Anadolu Kardiyol Derg. 2011 Feb;11(1):53-6. doi: 10.5152/akd.2011.010. Epub 2011 Jan 11, PMID: 21220246
Functional polymorphisms of cyclooxygenase-2 gene and risk for hepatocellular carcinoma. Akkiz H, Bayram S, Bekar A, Akgöllü E, Ülger Y
Mol Cell Biochem. 2011 Jan;347(1-2):201-8 PMID: 21042835
MDM2 promoter polymorphism is associated with increased susceptibility to hepatocellular carcinoma in Turkish population. Akkiz H, Sümbül A, Bayram S, Bekar A, Akgöllü E
Cancer Epidemiol. 2010 Aug;34(4):448-52. PMID: 20447891
No Association of NAD(P)H: quinone oxidoreductase 1 (NQO1) C609T Polymorphism and Risk of Hepatocellular Carcinoma Development in Turkish Subjects Akkiz H, Bayram S, Bekar A, Akgöllü E, Ülger Y, Kaya BY, Sandikçi M, Özdil B.
Asian Pacific J Cancer Prev, 11, 1051-1058. 2010 PMID:21133623
Relationship between functional polymorphism in the Aurora A gene and susceptibility of hepatocellular carcinoma. Akkiz H, Bayram S, Bekar A, Akgöllü E, Ozdil B.
J Viral Hepat. 2010 PMID: 20002563
Influence of CYP2C19 functional polymorphism on Helicobacter pylori eradication.
Ozdil B, Akkiz H, Bayram S, Bekar A, Akgöllü E, Sandıkçı M.
Turk J Gastroenterol. 2010 Mar;21(1):23-8 PMID: 20533108
Cyclin D1 G870A polymorphism is associated with an increased risk of hepatocellular carcinoma in the Turkish population: case-control study Akkiz H, Bayram S, Bekar A, Akgöllü E, Ozdil B.
Cancer Epidemiol. 2010 Jun;34(3):298-302. PMID: 20347627
Endoscopic alcohol injection therapy of giant gastric leiomyomas: an alternative method to surgery.
Ozdil B, Akkiz H, Kece C, Sandikci M
Can J Gastroenterol. 2010 Sep;24(9):533-5 PMID: 21152456
The Diagnostic Value of Endoscopic Balloon Catheter Usage for Detecting Early-Stage Primary Sclerosing Cholangitis in Endoscopic Retrograde Cholangiopancreatography: A Case Report
Ozdil B, Cosar A, Kece C, Sandikci M, Akkiz H
Case Rep Gastroenterol. 2010 Feb 2;4(1):1-5. PMID: 21103219
Infectious complications in the early postoperative period in liver transplant patients
Saner FH, Akkiz H, Canbay A.
Minerva Gastroenterol Dietol. 2010 Sep;56(3):355-65. PMID: 21037551
Potential benefits of combined N-acetylcysteine and ciprofloxacin therapy in partial biliary obstruction.
Ozdil B, Kece C, Cosar A, Akkiz H, Sandikci M
J Clin Pharmacol. 2010 Dec;50(12):1414-9. Epub 2010 Apr 13 PMID: 20388917
Management of an esophageal metallic stent obstructed by tumor progression: endoscopic alcohol injection therapy instead of restenting.
Ozdil B, Kece C, Akkiz H, Sandikci M, Cosar A.
Endoscopy. 2010;42 Suppl 2:E91. Epub 2010 Mar 1 PMID: 20195982
Giant subcutaneous HCC case occurring after percutaneous ethanol injection.
Ozdil B, Akkiz H, Sandikçi M, Keçe C, Coşar A.
Turk J Gastroenterol. 2009 Dec;20(4):301-2, PMID: 20084580</li
Recurrent hypersplenism caused by giant accessory spleen due to portal hypertension after splenectomia
Ozdil B, Akkiz H, Sandikci M, Kece C, Cosar A
Platelets. 2010 Feb;21(1):70-1 PMID: 19995153
Massive lower gastrointestinal hemorrhage secondary to rectal hemorrhoids in elderly patients receiving anticoagulant therapy: case series
Ozdil B, Akkiz H, Sandikci M, Kece C, Cosar A
Dıgestıve And Lıver Dısease, 2010 Sep;55(9):2693-4
Expression of mesenchymal, hematopoietic, and biliary cell markers in adult rat hepatocytes after partial hepatectomy.
Kara B, Daglioglu K, Doran F, Akkiz H, Sandikci M, Kara IO.
Transplant Proc. 2009 Dec;41(10):4401-4.PMID: 20005408
The significance of E266K polymorphism in the NOD1 gene on Helicobacter Pylori infection: an effective force on pathogenesis?
Kara B, Akkiz H, Doran F, Bayram S, Erken E, Gumurdullu Y, Sandikci M.
Clin Exp Med. 2009 Oct 31. PMID: 19882212
Apoptosis in selected liver diseases.
Kiliçarslan A, Kahraman A, Akkiz H, Yildiz Menziletoğlu S, Fingas CD, Gerken G, Canbay A.
Turk J Gastroenterol. 2009 Sep;20(3):171-9. Review.PMID: 19821198
G-308A TNF-alpha polymorphism is associated with an increased risk of hepatocellular carcinoma in the Turkish population: case-control study. Akkiz H, Bayram S, Bekar A, Ozdil B, Akgöllü E, Sümbül AT, Demiryürek H, Doran F.
Cancer Epidemiol. 2009 Oct;33(3-4):261-4. PMID: 19683483
Negative correlation between viral load and HBsAg levels in chronic HBV-infected patients.
Ozdil B, Cosar AM, Akkiz H, Sandikci MU, Kece C.
Arch Virol. 2009;154(9):1451-5. PMID: 19672557
Hepatocellular carcinoma pathogenesis: does PPAR alpha polymorphism have a role in hepatocarcinogenesis associated with HBV and HCV infections? Akkiz H.
Turk J Gastroenterol. 2008 Dec;19(4):231-3. PMID: 19119480
Expression of c-kit protooncogen in hepatitis B virus-induced chronic hepatitis, cirrhosis and hepatocellular carcinoma: has it a diagnostic role?
Kara B, Doran F, Kara IO, Akkiz H, Sandikci M.
Int J Clin Pract. 2008 Aug;62(8):1206-11. PMID: 18284441
Correlation of serum adiponectin levels and hepatic steatosis in hepatitis C virus genotype 1 infection.
Kara B, Gunesacar R, Doran F, Kara IO, Akkiz H.
Adv Ther. 2007 Sep-Oct;24(5):972-82. PMID: 18029322
Genotyping of hepatitis B virus isolated from chronic hepatitis B patients in the south of Turkey by DNA cycle-sequencing method.
Serin MS, Akkiz H, Abayli B, Oksuz M, Aslan G, Emekdas G.
Diagn Microbiol Infect Dis. 2005 Sep;53(1):57-60.PMID: 16054327
Expression of Fas antigen in liver tissue of patients with chronic hepatitis B and C.
Oksuz M, Akkiz H, Isiksal YF, Saydaogluc G, Serin M, Kayaselcuk F, Abayli B, Tuncer I.
Eur J Gastroenterol Hepatol. 2004 Mar;16(3):341-5.PMID: 15195900
Serum profile of T helper 1 and T helper 2 cytokines in patients with chronic hepatitis C virus infection.
Abayli B, Canataroğlu A, Akkiz H.
Turk J Gastroenterol. 2003 Mar;14(1):7-11.PMID: 14593531
Bullous pemphigoid and cholestatic hepatitis associated with Castleman’s disease.
Oksüz M, Ergün Y, Adam U, Gönlüşen G, Işiksal YF, Ergin M, Koçak F, Abayli B, Akkiz H, Akman A.
Turk J Gastroenterol. 2002 Dec;13(4):209-12, PMID: 16378307
Obesity and related parameters of non-alcoholic steatohepatitis.
Serin E, Akkiz H, Doran F, Gümürdülü Y, Gümürdülü D.
Turk J Gastroenterol. 2002 Jun;13(2):71-7, PMID: 16378280
Molecular characterization of a full genome Turkish hepatitis C virus 1b isolate (HCV-TR1): a predominant viral form in Turkey.
Yildiz E, Oztan A, Sar F, Pinarbasi E, Cetin-Atalay R, Akkiz H, Ozturk M.
Virus Genes. 2002 Oct;25(2):169-77.PMID: 12416679
Risk factors for hepatocellular carcinoma in Turkey.
Uzunalimoğlu O, Yurdaydin C, Cetinkaya H, Bozkaya H, Sahin T, Colakoğlu S, Tankurt E, Sarioğlu M, Ozenirler S, Akkiz H, Tözün N, Değertekin H, Okten A.
Dig Dis Sci. 2001 May;46(5):1022-8.PMID: 11341644
Circulating IL-2 and IL-10 in chronic active hepatitis C with respect to the response to IFN treatment.
Bozkaya H, Bozdayi AM, Aslan N, Türkay C, Sarioglu M, Cetinkaya H, Akdogan M, Cinar K, Erden E, Köse K, Sentürk H, Akkiz H, Karayalcin S, Yurdaydin C, Uzunalimoglu O.
Infection. 2000 Sep;28(5):309-13.PMID: 11073139
Endoscopic retrograde cholangiopancreatography in the diagnosis and management of choledochal cysts. Akkiz H, Colakoğlu SO, Ergün Y, Demiryürek H, Akinoğlu A, Tuncer I, Ozgür G, Hafta A.
HPB Surg. 1997;10(4):211-8; discussion 218-9.PMID: 9184874
Endoscopic management of biliary hydatid disease. Akkiz H, Akinoglu A, Colakoglu S, Demiryürek H, Yagmur O.
Can J Surg. 1996 Aug;39(4):287-92.PMID: 8697318
Hepatitis C virus genotypes in patients with hepatocellular carcinoma. Akkiz H, Colakoğlu S, Köksal F, Korkut H, Hafta A.
J Environ Pathol Toxicol Oncol. 1996;15(2-4):85-8.PMID: 9216790
Interferon-induced vitiligo in a patient with chronic viral hepatitis C infection.
Simsek H, Savas C, Akkiz H, Telatar H.
Dermatology. 1996;193(1):65-6. Review. PMID: 8864627
Presentation and role of peritoneoscopy in the diagnosis of tuberculous peritonitis.
Sandikçi MU, Colakoglu S, Ergun Y, Unal S, Akkiz H, Sandikçi S, Zorludemir S.
J Gastroenterol Hepatol. 1992 May-Jun;7(3):298-301. PMID: 1535231
Mortality-lowering effect of systemic corticosteroid therapy in severe tetanus.
Paydaş S, Akoğlu TF, Akkiz H, Ozer FL, Burgut R.
Clin Ther. 1988;10(3):276-80. PMID: 3078907